A revision of Resinicium collections (Basidiomycota, Hymenochaetales) from French Guiana and French West Indies is provided, and a new species, Resinicium grandisporum sp. nov., supported by morphological as well as phylogenetic analyses based on ITS rDNA sequences, is described and illustrated. An updated key of the genus Resinicium is also provided, which includes species previously described from outside of the studied area.