Four new Laboulbeniales parasitic on insects from French Guyana are described: Eucantharomyces egae, parasitic on Ega sp. (Coleoptera, Carabidae), Laboulbenia apotropinae, parasitic on Apotropina panamensis (Diptera, Chloropidae), Laboulbenia guyanensis, parasitic on Micratopus sp. (Coleoptera, Carabidae), and Stigmatomyces kotrbae, parasitic on Acrosticta apicalis (Diptera, Ulidiidae).