A new species of Boraginaceae, Heliotropium perrieri J.S. Mill., is described from Madagascar. It is a glabrous annual herb with flowers borne individually in the axils of leafy bracts and glabrous, reticulate nutlets and a member of Heliotropium sect. Orthostachys. It is known from only four collections, all made from the area just south of Mahajanga. As it is known from a single, highly threatened locality and has not been collected since 1929, it is provisionally listed as critically endangered.