A hyphomycetous fungus producing dark muriform conidia, was isolated as endophyte from trunk of Aquilaria crassna in Laos. The fungus was compared to morphologically similar genera, such as Annellophorella, Berkleasmium, Canalisporium, and Monodictys. Morphological evidence, however, excluded the fungal taxon from any of these genera. Phylogenetic analysis of combined small subunit, 5.8S, and large subunit ribosomal DNA sequence data placed the fungus within the order Savoryellales (Sordariomycetes, Hypocreomycetidae), but on a distinct terminal clade along with other groups of the order. Based on morphological and molecular phylogenetic evidence, we therefore established the genus Dematipyriforma to accommodate the taxon, which was named Dematipyriforma aquilaria.